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Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID
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DOI：10.1016/j.xcrm.2026.102946.png)
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Abstract
En 中文
• Combinatorial tetramer deep-profiling of viral-specific T cells in long COVID (LC) • LC features more cytolytic CD8+ T cells against SARS-CoV-2, CMV, and EBV • Females with LC exhibit most terminally differentiated cytolytic CD8+ T cells • Inability to resolve acute cytolytic CD8+ T cell response may be a feature of LC
Keywords:
long COVID
CD8+ T cells
SARS-CoV-2
EBV
CMV
granzyme
cytolytic
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