.png){kind=icon}
.png){kind=icon}
Return
PGAM1 rheostat in glycolysis and autophagy
.png){kind=icon}
PRE
AI
K
DOI：10.1038/s41556-026-02033-4.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
How tumour cells rewire metabolic processes in response to changing nutrient availability in the tumour microenvironment is complex. Here, Zhang et al. define a role for PGAM1 in promoting autophagy in response to nutrient deprivation that competes with its catalytic function in glycolysis, which may explain selection for PGAM1 overexpression in cancer.
Journal
IF:
19.1
Papers:
6.1K
Citations:
4.8W
Organization
Cited Papers