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Photosensitive biosensor array system using optical addressing without an addressing circuit on array biochips
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DOI：10.1063/1.3486179.png)
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Abstract
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This paper introduces a photosensitive biosensor array system with a simple photodiode array that detects photocurrent changes caused by reactions between probe and target molecules. Using optical addressing, the addressing circuit on the array chip is removed for low-cost application, and real cell addressing is achieved using an externally located computer-controllable light-emitting diode array module. The fabricated biosensor array chip shows a good dynamic range of 1-100 ng/mL under prostate-specific antigen detection, with an on-chip resolution of roughly 1 ng/mL. (c) 2010 American Institute of Physics. [doi:10.1063/1.3486179]
Keywords:
ELECTRICAL DETECTION
DNA-DETECTION
IMMUNODETECTION
NANOWIRES
SENSORS
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