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Photosynthetic chlorella-violet phosphorus nanosheet biohybrid alleviating tumor hypoxia for synergistic photodynamic-immunotherapy
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DOI：10.1016/j.bioadv.2026.215059.png)
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Abstract
En 中文
• A photosynthetic Chlorella-violet phosphorus biohybrid (Chl@VP) is constructed. • Chl@VP relieves tumor hypoxia via sustained photosynthetic O₂ supply. • VP-derived phosphate and ROS synergistically disrupt glycolytic tumor metabolism. • Chl@VP plus laser induces ICD and remodels the immunosuppressive TME. • This biohybrid integrates O₂ self-supply, metabolic intervention, and photo-immunotherapy.
Keywords:
Heterojunction
Photodynamic therapy
Immunotherapy
Tumor hypoxia
Photosynthetic chlorella
Violet phosphorus nanosheet
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6
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1.9K
Citations:
6.0K
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