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Pineal function: Impact of microarray analysis
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DOI：10.1016/j.mce.2009.07.010.png)
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Abstract
En 中文
Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function. Published by Elsevier Ireland Ltd.
Keywords:
Pineal
Microarray
Melatonin
Circadian rhythms
Cyclic AMP signaling
Immune response
Inflammation
MAP kinase
RNA splicing
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