Pneumonia

doi:10.1038/s41572-021-00259-0

Pneumonia

2021-04-08

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DOI：10.1038/s41572-021-00259-0

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Pneumonia is a common acute respiratory infection that affects the alveoli and distal airways; it is a major health problem and associated with high morbidity and short-term and long-term mortality in all age groups worldwide. Pneumonia is broadly divided into community-acquired pneumonia or hospital-acquired pneumonia. A large variety of microorganisms can cause pneumonia, including bacteria, respiratory viruses and fungi, and there are great geographical variations in their prevalence. Pneumonia occurs more commonly in susceptible individuals, including children of <5 years of age and older adults with prior chronic conditions. Development of the disease largely depends on the host immune response, with pathogen characteristics having a less prominent role. Individuals with pneumonia often present with respiratory and systemic symptoms, and diagnosis is based on both clinical presentation and radiological findings. It is crucial to identify the causative pathogens, as delayed and inadequate antimicrobial therapy can lead to poor outcomes. New antibiotic and non-antibiotic therapies, in addition to rapid and accurate diagnostic tests that can detect pathogens and antibiotic resistance will improve the management of pneumonia. Pneumonia is a respiratory infection of the distal airways; it can be acquired in the community or in the hospital, and it can be caused by several types of bacteria, viruses, fungi and other pathogens.

Keywords:

COMMUNITY-ACQUIRED PNEUMONIA

VENTILATOR-ASSOCIATED PNEUMONIA

INNATE LYMPHOID-CELLS

HYPOXEMIC RESPIRATORY-FAILURE

INFECTIOUS-DISEASES-SOCIETY

MEMORY T-CELLS

HOST-DEFENSE

RISK-FACTORS

HOSPITALIZED-PATIENTS

PSEUDOMONAS-AERUGINOSA

Pneumonia

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