1
Return

Poly-L-lactide-co-ε-caprolactone (PLCL) Reprograms Macrophage Metabolism and Mitochondrial Function to Promote Skin Wound Healing

delete2026-06-06
delete0
PRE
AI
J
Jiayin Yan
J
Jiacheng Liu
Y
Yumin Chen
Z
Zichun Liu
Y
Yang Sun
Y
Yichou Wei
R
Ruijia Chen
Y
Yangjie Xu
J
Jialin Hao *
C
Chen Chen *
Y
Ying He *
H
Huimin Zheng *
DOI：10.1016/j.tca.2026.180374delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
• PLCL could promote skin wound repair by remodeling the immune microenvironment. • Inflammatory responses of macrophages are suppressed by PLCL. • PLCL rescues mitochondrial damage and reverses metabolism from glycolysis to OXPHOS. • Metabolites such as succinate and prostaglandins in inflammatory macrophages are decreased by PLCL.

Journal

Thermochimica Acta cover
Thermochimica Acta
IF:
3.5
Papers:
9.5K
Citations:
1.9W

Organization

F
fudan university
Scholars:
11.3W
Papers: 7.6W
Citations: 121
S
Sun Yat-Sen University
Scholars:
7.8K
Papers: 2.1K
Citations: 0
S
Shanghai Engineering Research Center of Tooth Restoration and Regeneration
Scholars:
23
Papers: 13
Citations: 0
P
peking university
Scholars:
11.5W
Papers: 8.6W
Citations: 146
C
corliber
Scholars:
3
Papers: 2
Citations: 0
K
krirk university
Scholars:
193
Papers: 179
Citations: 8
Cited Papers

Cited Papers

Citing Papers

Citing Papers