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Polycaprolactone Mechanical Properties Evaluation for Biomedical Application
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DOI：10.4028/p-C3bQnm.png)
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Abstract
En 中文
The first polycaprolactone material experimental and clinical studies were published in 1960-1970, which proved its biocompatibility and determined the absence of toxic properties. At the same time it did not receive widespread use due to insufficient rigidity and strength compared to metal implants. For a long time, relatively solid materials were used to treat injuries to the musculoskeletal system segments. The progress in materials science, development of new sterilization methods has again changed the attitude towards biomaterial implants and has attracted the attention of clinicians. In this regard, the development of predictive modeling methods to determine effective mechanical properties and optimal geometric structure of porous biomedical materials is an important task. Modeling the internal architecture of porous materials and their properties by the finite element method using computed tomography data is as close as possible to the real picture, but it is quite laborious to apply directly to large-sized scaffolds. Properties of such materials largely depend on the technology of their manufacture and processing, the geometric dimensions and cell shape. In this regard, the development and improvement of analytical methods for assessing properties of cellular structures remains relevant. The aim of this study is determining polycaprolactone effective elastic modulus based on modified Gibson-Ashby open-cell model as an implant material and osteochondral defects treatment. A practical analytical method for estimating the elastic modulus of a cellular material regardless of the scaffold volume and shape is proposed. Calculations are performed for polycaprolactone produced using selective laser sintering technology. A comparative analysis of the obtained results with experimental studies of other authors is carried out. The results can be used for evaluation analysis and calculations of medical devices strength and stiffness made of porous polycaprolactone for the bone defects treatment.
Keywords:
biocompatible material
polycaprolactone
Gibson-Ashby model
elastic modulus
open porosity
Journal
J
IF:
0.5
Papers:
23
Citations:
270