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Polyomavirus-Specific T Cells in Progressive Multifocal Leukoencephalopathy: A Multicenter Retrospective Analysis
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DOI：10.1016/j.jtct.2026.06.015.png)
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Abstract
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• Polyomavirus-specific T-cell (PyVST) transfer offers a safe and promising therapeutic option for patients with progressive multifocal leukoencephalopathy. • Questions remain regarding the optimal approach for PyVST generation, recipient and PyVST characteristics to achieve treatment success.
Keywords:
JC polyomavirus
Progressive multifocal leukoencephalopathy
cellular therapy
virus-specific T cells
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