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Polystyrene Nanoplastics Exacerbate Systemic Lupus Erythematosus via Neutrophil Extracellular Traps (NETs) Formation

delete2026-06-06
delete0
PRE
AI
W
Wanlan Jiang
M
Min Ni
M
Min Wu
T
Ting Xu
Y
Yilin Liu
C
Chenxian Zhu
J
Jianhao Wang *
S
Songwei Lv *
DOI：10.1016/j.envpol.2026.128509delete
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Abstract

Abstract

En 中文
• Environmental PS-NPs exposure exacerbates SLE via NETs formation • Neutrophils internalize PS-NPs, triggering robust NETosis and cell death • Human-equivalent oral PS-NPs doses profoundly aggravate murine lupus • PS-NPs exposure severely disrupts lipid and amino acid metabolic homeostasis • Pharmacological NETs inhibition reverses NP-exacerbated immunotoxicity

Journal

Environmental Pollution cover
Environmental Pollution
IF:
7.3
Papers:
2.6W
Citations:
13.8W

Organization

T
The First People's Hospital of Changzhou
Scholars:
35
Papers: 15
Citations: 421
C
Changzhou University
Scholars:
1.3W
Papers: 8.1K
Citations: 1.1W
C
Changzhou Maternal and Child Health Care Hospital
Scholars:
31
Papers: 11
Citations: 1
S
Suzhou University
Scholars:
1.0K
Papers: 542
Citations: 17
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