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Porphyromonas gingivalis Inhibits Ferroptosis and Promotes Malignant Phenotype in Oral Squamous Cell Carcinoma Cells via Upregulation of SIRT5

delete2025-10-07
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PRE
AI
Y
Yiqun Jia
H
Hongxia You
W
Weixuan Chen *
Y
Yuyan Zheng *
DOI:10.1016/j.micinf.2025.105564delete
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Abstract

Abstract

En 中文
Oral squamous cell carcinoma (OSCC) exhibits aggressive behavior and poor prognosis. Porphyromonas gingivalis (P. gingivalis) affects the tumor microenvironment, but its role in ferroptosis inhibition in OSCC remains unclear. This study explores the impact of P. gingivalis on ferroptosis through SIRT5 upregulation.

Journal

Microbes and Infection cover
Microbes and Infection
IF:
2.7
Papers:
130
Citations:
6.1K

Organization

S
Southern University of Science and Technology
Scholars:
5.2K
Papers: 2.1K
Citations: 34
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