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Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neurodegenerative pathologies
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DOI：10.1002/alz.71649.png)
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Abstract
En 中文
The impact of different neuropathologies on deep brain structures remains to be understood. We examine subcortical and limbic volumetry in neurodegenerative diseases involving phosphorylated tau (p-tau), α-synuclein, and transactive response DNA binding protein 43 (TDP-43).
Keywords:
ADRD
alzheimer's disease
alzheimer's disease and related dementias
copathologies
entorhinal cortex
ex vivo magnetic resonance imaging (MRI)
frontotemporal lobar degeneration with transactive response DNA binding protein 43 (FTLD-TDP)
FTLD-tau
lewy body dementia
neuroimaging
neuropathologies
postmortem imaging
subcortical structures
synuclein
tau
TDP-43
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