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Potential Drug-Drug Interactions With Nirmatrelvir/Ritonavir Among Long-Term Care Facility Residents

delete2026-07-07
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OA
AI
M
Marzan A. Khan *
L
Lori A. Daiello
S
Sarah D. Berry
D
Daniel A. Harris
Y
Yu-Chia (Sam) Hsu
C
Charles E. Leonard
A
Andrew R. Zullo
DOI:10.1016/j.jamda.2026.106365delete
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Abstract

Abstract

En 中文
Nirmatrelvir/ritonavir (Paxlovid) is an oral antiviral for COVID-19. Although effective, its use is complicated by clinically important potential drug-drug interactions (DDIs). Long-term care facility (LTCF) residents are especially vulnerable to both COVID-19 and the adverse effects of potential DDIs because of advanced age, multimorbidity, and polypharmacy. The objective of this study was to quantify the prevalence and duration of potential DDIs among US LTCF residents administered nirmatrelvir/ritonavir.
Keywords:
COVID-19
drug-drug interaction
long-term care facility residents
nirmatrelvir/ritonavir
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Journal of the American Medical Directors Association cover
Journal of the American Medical Directors Association
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3.8
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5.7K
Citations:
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