.png){kind=icon}
Return
Primary hepatic angiosarcoma
.png){kind=icon}
PRE
AI
DOI：10.1016/j.ejso.2015.04.022.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Primary hepatic angiosarcoma is a rare, aggressive tumor; composed of spindle or pleomorphic cells that line, or grow into, the lumina of pre-existing vascular spaces like sinusoids and terminal hepatic venules; with only about 200 cases diagnosed annually worldwide but it is the most common primary malignant mesenchymal tumor of the liver in adults and accounts for 2% of all primary hepatic malignancies. HAS occurs in association with known chemical carcinogens, but 75% of the tumors have no known etiology. Patients present with vague symptoms like abdominal pain, weight loss, fatigue or an abdominal mass. Hepatic angiosarcoma is usually multicentric and involves both lobes, entire liver may also found to be involved. CD31 is the most reliable marker. These tumors lack specific features on imaging, so, pathological diagnosis is necessary. There are no established treatment guidelines because of low frequency and aggressive nature of tumor, chemotherapy is only palliative, liver resection is indicated for solitary mass and liver transplant is contraindicated. The aim of this article is to comprehensively review all the available literature and to present detailed information and an update on primary hepatic angiosarcoma. (C) 2015 Elsevier Ltd. All rights reserved.
Keywords:
Primary hepatic angiosarcoma
Non-specific symptoms
Difficult and delayed diagnosis
No treatment guidelines
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
2.9
Papers:
6.7K
Citations:
1.3W
Organization
Cited Papers
Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma.png)
ANNALS OF ONCOLOGY
OAAI
ANNALS OF ONCOLOGYIF65.4
OAAIShareSaveShareSaveShareSave
ShareSaveShareSaveContrast-enhanced ultrasound study of primary hepatic angiosarcoma: A pitfall of non-enhancement
PREAI
ShareSaveRelationship of Prostate-Specific Antigen Velocity to Histologic Findings in a Prostate Cancer Screening ProgramUrology
UrologyIF0
PREAI
ShareSaveShareSaveO-acetylation of typhoid capsular polysaccharide confers polysaccharide rigidity and immunodominance by masking additional epitopesVaccineOAAI
VaccineIF0
OAAIShareSave
View more