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Prioritizing Tuberculosis Preventive Therapy for IGRA-negative People Living with HIV Initiating Antiretroviral Therapy

delete2026-06-11
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OA
AI
W
Wenjun Kang
Y
Yueming Shao
Z
Zhenyan Wang
T
Tangkai Qi
J
Jianjun Sun
J
Junyang Yang
S
Shuibao Xu
W
Wei Song
Y
Youming Chen
Y
Yang Tang
L
Li Liu
R
Renfang Zhang
J
Jun Chen *
DOI:10.1016/j.jiph.2026.103284delete
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Abstract

Abstract

En 中文
Tuberculosis (TB) remains the leading cause of death among people living with HIV (PLWH). While tuberculosis preventive treatment (TPT) is universally recommended for PLWH with latent TB infection (LTBI), its necessity for interferon-gamma release assay (IGRA)-negative individuals initiating antiretroviral therapy (ART) is controversial. Therefore, this study aimed to investigate whether TPT is necessary in this specific population.
Keywords:
HIV
Latent tuberculosis
IGRA
Tuberculosis preventive treatment
risk stratification
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Journal

Journal of Infection and Public Health cover
Journal of Infection and Public Health
IF:
4
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570
Citations:
7.0K

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