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Probing ligand selectivity in pathogens

delete2023-12-21
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OA
AI
B
Bryan VanSchouwen
G
Giuseppe Melacini *
DOI：10.7554/eLife.94720delete
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Abstract

Abstract

En 中文
Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other organisms?
Keywords:
Protein kinase A
ligand selectivity
trypanosomatid pathogens
T. brucei
T. cruzi
L. donovani
Other

Journal

eLife cover
eLife
IF:
0
Papers:
1.8W
Citations:
16

Organization

M
McMaster University
Scholars:
3.6W
Papers: 3.3W
Citations: 4.4W