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Process design enhancement of a pilot-scale supercritical-CO2 extraction plant for efficient recovery of wheat germ bioactives
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DOI：10.1016/j.jcou.2026.103436.png)
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Abstract
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• CO₂ subcooling ensured liquid feed and improved pump stability at start-up. • CO₂ density governed kinetics; max oil recovery reached 6.9 wt%. • FAME and α-tocopherol were preserved; no oxidation was detected in extracts. • Back-pressure valve re-tuning guaranteed limited CO2 density fluctuations. • SC-CO₂ energy demand comparable to hexane, with a more compact set-up.
Keywords:
Supercritical fluid
Bioactive compounds
Scale-up
Process optimization
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