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Programmable DNA switches and their applications
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DOI：10.1039/c7nr07348h.png)
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Abstract
En 中文
DNA switches are ideally suited for numerous nanotechnological applications, and increasing efforts are being directed toward their engineering. In this review, we discuss how to engineer these switches starting from the selection of a specific DNA-based recognition element, to its adaptation and optimisation into a switch, with applications ranging from sensing to drug delivery, smart materials, molecular transporters, logic gates and others. We provide many examples showcasing their high programmability and recent advances towards their real life applications. We conclude with a short perspective on this exciting emerging field.
Keywords:
APTAMER-BASED SENSORS
HYBRIDIZATION CHAIN-REACTION
ENHANCED RAMAN-SPECTROSCOPY
G-QUADRUPLEX DNA
STRAND-DISPLACEMENT-REACTIONS
ROLLING CIRCLE AMPLIFICATION
CELL GENE-EXPRESSION
HOMOGENEOUS ELECTROCHEMICAL STRATEGY
CONSTITUTIONAL DYNAMIC NETWORKS
MODIFIED GOLD NANOPARTICLES
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