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Progress in metal complex-based nanoplatform for cancer sonodynamic immunotherapy: mechanistic insights, structural designs, challenges and perspectives

delete2026-05-07
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PRE
AI
H
Han Xu
M
Mengjie Hou
F
Fangmian Wei *
X
Xing-Can Shen *
DOI:10.1016/j.ccr.2026.218051delete
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Abstract

Abstract

En 中文
• The sonosensitive pathways and immunomodulatory mechanisms elicited by metal complex-based nanoplatforms for cancer SDIT are highlighted. • This review summarizes recent advances in metal complex-based nanoplatforms for cancer SDIT and their state-of-the-art structural design strategies. • The existing challenges and future perspectives about the structure-activity relationships and clinical translation of metal complex-based nanoplatform-mediated SDIT are outlined herein.
Keywords:
metal complex-based nanoplatform
sonodynamic immunotherapy
cancer therapy
structural design
mechanistic insights

Journal

Coordination Chemistry Reviews cover
Coordination Chemistry Reviews
IF:
23.5
Papers:
8.9K
Citations:
7.3W

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