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Pulmonological issues
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DOI：10.1016/j.cppeds.2022.101313.png)
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Abstract
En 中文
Pediatric leukodystrophies are rare neurodegenerative diseases involving multiple systems. Each form has unique neurologic features but are characterized by encephalopathy with accompanying impairments evidenced in reflexes, muscle tone and movement control. Weakness of expiratory, inspiratory, and upper airway muscles may lead to impaired airway secretion clearance resulting in recurrent respiratory infections, dysphagia, sleep-disordered breathing, restrictive lung disease, and ultimately chronic respiratory insufficiency.
Keywords:
POSITIVE-PRESSURE VENTILATION
PRACTICE GUIDELINE EFFECTIVENESS
GLYCOPYRROLATE ORAL SOLUTION
DUCHENNE MUSCULAR-DYSTROPHY
AIRWAY CLEARANCE THERAPIES
NONINVASIVE VENTILATION
MECHANICAL VENTILATION
COUGH-AUGMENTATION
CHEST-WALL
INSUFFLATION-EXSUFFLATION
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