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Punicalagin Enhances Odontogenic Differentiation and Reparative Dentin Formation via Wnt/β-Catenin Signalling
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DOI：10.1016/j.identj.2026.109801.png)
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Abstract
En 中文
Punicalagin (PCG), a natural polyphenol derived from pomegranate peel, possesses well-established antibacterial and anti-inflammatory properties. However, whether PCG promotes odontogenic differentiation of human dental pulp stem cells (DPSCs) remains unclear. This study investigated the effects of PCG on odontogenic differentiation and reparative dentin formation and further explored the underlying molecular mechanism.
Keywords:
Punicalagin
Dental pulp stem cells
Odontogenic differentiation
Wnt/β-catenin
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