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Putting proteins in context
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AI
DOI：10.1016/j.cels.2024.09.009.png)
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Abstract
En 中文
Proteins exhibit cell-type-specific functions and interactions, yet most ways of representing proteins lack any biological or environmental context. To address this gap, recent work by Li et al.1 introduces PINNACLE, a geometric deep learning approach that generates contextualized representations of proteins by combined analysis of protein interactions and multiorgan single-cell transcriptomics.
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