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Quantitative assessment method for irreversible electroporation based on the distribution of relaxation times
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DOI：10.1016/j.elecom.2026.108185.png)
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Abstract
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• The article introduces the use of the distribution of relaxation times (DRT) to evaluate irreversible electroporation (IRE) tissue ablation. • DRT efficiently separates between multiple overlapping processes. • After ablation, both the area and height of all seven peaks are significantly reduced, consistent with the ion redistribution phenomenon caused by membrane perforation. • A Gaussian Process Regression (GPR) framework was employed to quantitatively assess the ablation depth. • The four-electrode impedance detection technique effectively mitigates the interference from contact impedance.
Keywords:
Distribution of relaxation times
Irreversible electroporation
Impedance spectroscopy
Equivalent circuit model
Gaussian process regression
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