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Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation

delete2026-06-18
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PRE
AI
J
James W. Swann
J
Jun Hou Fung
Z
Ziwei Chen
O
Oakley C. Olson
A
Amélie Collins
T
Tenzin Lhakhang
M
Melissa A. Proven
R
Ruiyuan Zhang
R
Raul Rabadan *
E
Emmanuelle Passegué *
DOI：10.1016/j.stem.2026.05.007delete
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Abstract

Abstract

En 中文
• New HemaScribe method for murine HSPC annotation in scRNA-seq datasets • Different emergency myelopoiesis (EM) inducers target different HSPC populations • Unique and shared transcriptional modules are enacted by different EM inducers • A myeloid progenitor EM module informs outcomes in human acute myeloid leukemia

Journal

Cell Stem Cell cover
Cell Stem Cell
IF:
20.4
Papers:
3.6K
Citations:
3.1W

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C
columbia university
Scholars:
4.4K
Papers: 1.9K
Citations: 2
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