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delete2026-08-20
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Daniel I. Sessler
DOI:10.1016/j.bja.2026.07.013delete
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Abstract

Abstract

En 中文
At some level, intraoperative arterial hypotension causes organ injury. Sicova and colleagues present a meta-analysis of 9 trials in 14 658 patients that compared mortality in patients randomised to routine blood pressure management (with most mean arterial pressures >65 mm Hg) or defined higher pressures. The results were neutral, providing compelling evidence that mean pressures ≥65 mm Hg are generally safe even in older patients with baseline hypertension and other cardiovascular risk factors, and that targeting higher pressures does not reduce organ injury or mortality.

Journal

British Journal of Anaesthesia cover
British Journal of Anaesthesia
IF:
9.2
Papers:
2.3W
Citations:
2.9W

Organization

No organization information available
Cited Papers

Cited Papers

Proactive vs Reactive Treatment of Hypotension During Surgery
errJAMA
IF0
err2025-12-02
err0
PREAI
errKant,Matthijs; van Klei,Wilton A.; Hollmann,Markus W.; de Klerk,Eline S.; Otterspoor,Luuk C.; Besselink,Marc G.; Kappen,Teus H.; Veelo,Denise P.; ; Akkermans,Annemarie; Bastiaanse,Tim; Bemelman,Wilhelmus A.; van Berge Henegouwen,Mark I.; Bergsma,J. Eelco; Bot,Maarten; Coert,J. Henk; Cromheecke,Geert-Jan E.; Daams,Freek; Hazenberg,Constantijn; Hietbrink,Falco; Hompes,Roel; Huijzer,Marlous; Huirne,Judith; Immink,Rogier V.; Janmaat,Yvonne C.; Jongkind,Vincent; Kievit,Arthur J.; de Kort,Laetitia M.O.; Kroon,Olaf; van den Munckhof,Pepijn; van Rhijn,Lodewijk W.; Robe,Pierre A.J.T.; Roovers,Johannes P.; Ruurda,Jelle P.; Saouti,Rachid; Schafroth,Matthias U.; Schuurman,Rick; van Spronsen,Erik; Stokroos,Robert J.; Strypet,Magnus; Stufkens,Sjoerd A.; Tahanatoe,Sandra J.; Terwindt,Lotte E.; Vernooij,Lisette; Sperna Weiland,Niek H.; Wijnberge,Marije; Witziers,Jannie; Zweemer,Ronald P.
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Associations between intraoperative hypotension, duration of surgery and postoperative myocardial injury after noncardiac surgery: a retrospective single-centre cohort study
err2022-10-01
err23
errOAAI
errWesselink, Esther M.; Wagemakers, Sjors H.; Van Waes, Judith A. R.; Wanderer, Jonathan P.; Van Klei, Wilton A.; Kappen, Teus H.
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Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery A Randomized Clinical Trial
err2017-10-10
err560
errOAAI
errFutier, Emmanuel; Lefrant, Jean-Yves; Guinot, Pierre-Gregoire; Godet, Thomas; Lorne, Emmanuel; Cuvillon, Philippe; Bertran, Sebastien; Leone, Marc; Pastene, Bruno; Piriou, Vincent; Molliex, Serge; Albanese, Jacques; Julia, Jean-Michel; Tavernier, Benoit; Imhoff, Etienne; Bazin, Jean-Etienne; Constantin, Jean-Michel; Pereira, Bruno; Jaber, Samir
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Low Versus High Blood Pressure Targets in Critically Ill and Surgical Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
err2024-04-24
err8
PREAI
errD'Amico, Filippo; Pruna, Alessandro; Putowski, Zbigniew; Dormio, Sara; Ajello, Silvia; Scandroglio, Anna Mara; Lee, Todd C.; Zangrillo, Alberto; Landoni, Giovanni
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Intraoperative hypotension and adverse postoperative outcomes: a systematic review and meta-analysis of randomised controlled trials
err2026-08-01
err0
PREAI
errSicova,Marc; Alkadri,Jamal; Sibley,Daniel; Schenk,Jimmy; Kant,Matthijs; Kappen,Teus; Veelo,Denise P.; McCluskey,Stuart A.; Mina,Daniel Santa; Randall,Ian; van Klei,Wilton A.
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Intensive vs Conventional Intraoperative Blood Pressure Management on Cardiovascular Events After Major Abdominal Surgery
errJACC
IF0
err2025-09-15
err0
PREAI
errBingcheng Zhao; Jiaqiang Zhang; Yishan Xie; Zhuoxi Wu; Gaofeng Guo; Shaohui Lei; Jiaming Liu; Huamin Liu; Jian Liu; Weifeng Liu; Cai Li; Yangyang Lian; Yuting Tan; Dongxin Wang; Hong Li; Daniel I. Sessler; Kexuan Liu
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HIgh versus STAndard blood Pressure target in hypertensive high-risk patients undergoing elective major abdominal surgery: the HISTAP multicenter randomized clinical trial
err2026-06-29
err0
PREAI
errMaurizio Cecconi; Andrea Cortegiani; Alberto Noto; Giovanni Sotgiu; Massimo Antonelli; Marco Anderloni; Ilaria Barbaresco; Federico Bizzarri; Andrea Brunati; Iacopo Cappellini; Gianmaria Cammarota; Mariagiovanna Caporale; Francesca Collino; Monica Cuschera; Irene Coloretti; Katia Donadello; Lorenzo Foti; Luciano Frassanito; Diego Fiume; Massimo Girardis; Camilla L’Acqua; Gianluigi Lauro; Salvatore Maurizio Maggiore; Sandra Magnoni; Lucia Mirabella; Giovanni Misseri; Sara Miori; Guia Margherita Matronola; Gaia Pavan; Tommaso Pellis; Federico Piccioni; Mariangela Valentina Puci; Sara Pugliese; Bruno Romanò; Andrea Russo; Nicolò Samuelli; Vito Torrano; Andrea Viani; Samir Jaber; Elie Azoulay; Stefano Romagnoli; Antonio Messina
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Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery
err2019-05-01
err390
errOAAI
errSessler, Daniel I.; Bloomstone, Joshua A.; Aronson, Solomon; Berry, Colin; Gan, Tong J.; Kellum, John A.; Plumb, James; Mythen, Monty G.; Grocott, Michael P. W.; Edwards, Mark R.; Miller, Timothy E.
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