.png){kind=icon}
.png){kind=icon}
Return
Radiofrequency-responsive poly(combretastatin ionic liquid) nanogels for themo-boosting trans-arterial vascular disruption-embolization
.png){kind=icon}
PRE
AI
L
B
X
M
刘
Z
C
杨
Y
DOI：10.1016/j.nantod.2026.103130.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• An RF-responsive PIV·CA nanogel is developed for thermo-boosting TAVDE against HCC. • PIV·CA exhibits RF-responsive heating, pulsatile CA4P release and thermosensitive gelation for TAVDE-RFA synergy. • RF field shockingly amplifies PIV·CA cytotoxicity by ~22-fold via enhanced tubulin interaction and G2/M phase arrest. • RF boosts mitochondrial damage, ROS generation and ICD, evoking antitumor immunity and suppressing metastasis. • RF-energized CA4P disrupts tumor vasculature, improves intratumoral penetration, suppresses tumor growth.
Journal
IF:
10.9
Papers:
3.0K
Citations:
2.1W
Organization
Cited Papers