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RANDOMIZATION-BASED CAUSAL INFERENCE FROM SPLIT-PLOT DESIGNS

delete2018-10-01
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OA
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A
Anqi Zhao *
丁鹏 cover
丁鹏 (Peng Ding)
T
Tirthankar Dasgupta
DOI:10.1214/17-AOS1605delete
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Abstract

Abstract

En 中文
Under the potential outcomes framework, we propose a randomization based estimation procedure for causal inference from split-plot designs, with special emphasis on 2(2) designs that naturally arise in many social, behavioral and biomedical experiments. Point estimators of factorial effects are obtained and their sampling variances are derived in closed form as linear combinations of the between- and within-group covariances of the potential outcomes. Results are compared to those under complete randomization as measures of design efficiency. Conservative estimators of these sampling variances are proposed. Connection of the randomization-based approach to inference based on the linear mixed effects model is explored. Results on sampling variances of point estimators and their estimators are extended to general split-plot designs. The superiority over existing model-based alternatives in frequency coverage properties is reported under a variety of simulation settings for both binary and continuous outcomes.
Keywords:
Between-whole-plot additivity
model-based inference
Neymanian inference
potential outcomes framework
projection matrix
within-whole-plot additivity
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Annals of Statistics cover
Annals of Statistics
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