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Rationally modulating the dipole moment of quinoxaline imide-derivative-based small molecular photothermal agent for enhanced photothermal antitumor therapy
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DOI：10.1016/j.dyepig.2026.113836.png)
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Abstract
En 中文
• An asymmetric small molecular photothermal agent (QIPV-4F) was developed by incorporating vinylene bridge into its symmetric analogue QIP-4F. • QIPV-4F with a boosted dipole moment, enlarged intermolecular spacing and higher reorganization energy exhibited a PCE of 57%, 1.6-fold better than QIP-4F. • QIPV-4F NPs demonstrated excellent photothermal therapeutic effects in vivo and in vitro experiments.
Keywords:
QIPV-4F
photothermal agent
dipole moment
antitumor therapy
quinoxaline imide
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4.2
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1.3W
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2.9W
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