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Reaching the limit
DOI:10.7554/eLife.39804.png)
Abstract
En 中文
How many copies of a protein can be made before it becomes toxic to the cell?
Keywords:
DOSAGE SENSITIVITY
PROTEIN
EXPRESSION
COST
Journal
IF:
0
Papers:
1.8W
Citations:
16
Organization
Cited Papers
The cost of expression of Escherichia coli lac operon proteins is in the process, not in the products
GENETICS
IF5.1
Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method
GENOME RESEARCH
IF5.5
A Concentration-Dependent Liquid Phase Separation Can Cause Toxicity upon Increased Protein Expression
CELL REPORTS
IF6.9
Estimating the protein burden limit of yeast cells by measuring the expression limits of glycolytic proteins
ELIFE
IF0
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