.png){kind=icon}
.png){kind=icon}
Return
Reactors for flow biocatalysis: classification; performance; and prospects
.png){kind=icon}
PRE
AI
DOI：10.1039/D5RE00260E.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Flow biocatalysis has emerged as a promising alternative to conventional batch processes; offering improved energy efficiency; enhanced reaction control; and reduced waste generation. This review presents recent advances in flow biocatalysis; with a focus on system design; enzyme handling strategies; and catalytic performance. Based on enzyme retention; these systems are broadly categorized into flow biocatalysis using free enzymes; where enzymes are co-eluted with the product; and flow biocatalysis using immobilized enzymes; where enzymes are immobilized within the reactor. The latter are further divided into wall-coated and packed systems; including multilayered coatings; grafted surfaces; and monolithic structures. Representative applications in pharmaceutical synthesis; fine chemicals; and environmental remediation are discussed to illustrate the practical impact of these technologies. Finally; future perspectives are outlined; highlighting the potential of carrier material innovation; reactor design optimization; and data-driven process control to further drive the development of flow biocatalysis.
Journal
IF:
3.1
Papers:
1.9K
Citations:
5.0K