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Real-World Use of Evinacumab at the University of Pennsylvania Health Systems

delete2026-06-10
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PRE
AI
M
Midori Hupfeld
R
Rebecca Burdett
A
Archna Bajaj
DOI:10.1016/j.jacl.2026.05.191delete
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Abstract

Abstract

En 中文
Evinacumab is a monoclonal antibody targeting angiopoietin-like protein 3 (ANGPTL3) that reduces low-density lipoprotein cholesterol (LDL-C) levels by ~50% when used with standard lipid-lowering therapies in homozygous familial hypercholesterolemia (HoFH) patients. Food and Drug Administration (FDA) approved in February 2021, it is administered via monthly intravenous infusions.

Journal

Journal of Clinical Lipidology cover
Journal of Clinical Lipidology
IF:
4.6
Papers:
2.5K
Citations:
4.3K

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