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Reduced ATXN1 expression as an adverse prognostic indicator in Acute myeloid leukemia
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DOI：10.1016/j.gene.2026.150295.png)
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Abstract
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• Low ATXN1 expression indicates adverse prognosis and poor overall survival in AML. • ATXN1 overexpression suppresses AML cell proliferation and colony formation. • ATXN1 expression positively correlates with monocyte infiltration and immune activity. • ATXN1-related genes are enriched in immune regulation and metabolic pathways.
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