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Reduced Gut Microbiome Alpha Diversity Associates with Depressive Symptom Severity and Somatic Symptom Burden in Major Depression

delete2026-04-22
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Abdul Rahman Ghanam *
S
Sören Gatermann
G
Georg Juckel
DOI:10.1016/j.jpsychires.2026.04.022delete
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Abstract

Abstract

En 中文
Alteration in gut microbiome have been increasingly linked to many psychiatric disorders inclusive depression. However, findings regarding microbiome diversity in depression remain inconsistent. Differences in depression subtypes, particularly the somatic versus affective symptoms profiles may partly explain this heterogeneity in previous results.
Keywords:
Gut microbiota
Alpha diversity
16S rRNA sequencing
Major depressive disorder
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Journal

Journal of Psychiatric Research cover
Journal of Psychiatric Research
IF:
3.2
Papers:
7.9K
Citations:
2.4W

Organization

R
Ruhr-Universität Bochum
Scholars:
295
Papers: 116
Citations: 0
R
Ruhr University Bochum
Scholars:
492
Papers: 230
Citations: 2.1W