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Reprogramming assembly lines
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DOI：10.1038/nchem.2941.png)
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Abstract
En 中文
Rational engineering of biosynthetic assembly lines for production of new compounds is an attractive prospect, yet it presents many challenges. Learning from biology, some of the rules for expanding the chemical diversity of non-ribosomal peptides have been uncovered in two recent studies.
Keywords:
NONRIBOSOMAL PEPTIDE SYNTHETASE
AMINO-ACID RECOGNITION
CRYSTAL-STRUCTURE
MECHANISM
DOMAINS
MODULE
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