Return
Reprogramming the Tumor Microenvironment with Oxygen-Driven Nanomotors for Cuproptosis-Enhanced Immunotherapy
X
S
Y
C
M
Y
Z
L
Y
Z
L
J
Q
DOI:10.1016/j.mtbio.2026.103540.png)
Abstract
En 中文
• A self-propelling and oxygen-generating nanomotor is engineered for active tumor penetration and hypoxia alleviation. • Synergistic photothermal-cuproptosis therapy triggers potent immunogenic cell death. • Multi-stimuli-responsive drug release ensures spatiotemporal precision. • Robust systemic anti-tumor immunity suppresses both primary and metastatic tumors. • Initiates an immunomodulatory chain reaction triggered by cuproptosis to reverse immunosuppression.
Keywords:
cancer immunotherapy
tumor microenvironment
cuproptosis
nanomotors
photothermal therapy
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
10.2
Papers:
3.6K
Citations:
9.5K
