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Resveratrol attenuates Cr(VI)-induced ferroptosis through SIRT3 activation in nephrocytes and in vivo

delete2026-08-11
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OA
AI
M
Muzi Li
P
Pu Zhang
Z
Zhiyuan Lu
C
Changxi Qi
X
Xiaozhou Wang
H
Huahua Chen
J
Jiayi Li
G
Guodong Cheng
X
Xiaona Zhao *
J
Jianzhu Liu *
DOI:10.1016/j.ecoenv.2026.120646delete
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Abstract

Abstract

En 中文
• Cr(VI) exposure induces ferroptosis in nephrocyte by the activation of oxidative stress. • SIRT3 is essential for the regulation of ferroptosis caused by Cr(VI) in nephrocyte. • Resveratrol inhibits ferroptosis in nephrocyte caused by Cr(VI) exposure by activating SIRT3.
Keywords:
Ferroptosis
Resveratrol
SIRT3
Cr(VI)
Oxidative stress
Protein expression
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Journal

E
Ecotoxicology and Environmental Safety
IF:
6.1
Papers:
1.8W
Citations:
6.9W

Organization

S
shandong agricultural university
Scholars:
3.8K
Papers: 1.0K
Citations: 139
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