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Revised safety evaluation of the food enzyme triacylglycerol lipase from the non-genetically modified Burkholderia stagnalis strain PL266-QLM

delete2026-07-07
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OA
AI
E
EFSA Panel on Food Enzymes (FEZ)
H
Holger Zorn
J
José Manuel Barat Baviera
C
Claudia Bolognesi
F
Francesco Catania
G
Gabriele Gadermaier
R
Ralf Greiner
B
Baltasar Mayo
A
Alicja Mortensen
Y
Yrjö Henrik Roos
M
Marize L. M. Solano
H
Henk Van Loveren
L
Laurence Vernis
C
Cristina Andreoli
A
Andrea Terron
A
Andrey Yurkov
J
Jaime Aguilera
N
Natalia Kovalkovicova
C
Cristina Fernandez-Fraguas
D
Daniele Cavanna
Y
Yi Liu
DOI:10.2903/j.efsa.2026.10174delete
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Abstract

Abstract

En 中文
The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase EC 3.1.1.3) is produced with the non-genetically modified Burkholderia stagnalis strain PL266-QLM by Meito Sangyo Co., Ltd. In a previous evaluation, the Panel had concluded that this food enzyme posed a risk of promoting the spread of antimicrobial resistance genes. As a follow-up, the applicant submitted a new application for this enzyme intended to be used in three food manufacturing processes. Since residual amounts of food enzyme–total organic solids (TOS) are removed in these three processes, a dietary exposure was not calculated. The new data provided confirmed the presence of DNA from the production strain in the food enzyme. Based on the new and the previously evaluated data, the Panel reiterates the previous conclusion that this food enzyme poses a risk of promoting the spread of antimicrobial resistance genes in the environment, and therefore its use cannot be considered safe.
Keywords:
Burkholderia stagnalis
EC 3.1.1.3
EFSA-Q-2024-00084
food enzyme
lipase
triacylglycerol acylhydrolase
triacylglycerol lipase
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EFSA Journal
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