.png){kind=icon}
.png){kind=icon}
Return
Right hemi-alexia
.png){kind=icon}
PRE
AI
DOI：10.1016/j.cortex.2022.09.015.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
While pure alexia was long considered a disconnection syndrome, it may also be a selective visual word agnosia due to damage to the visual word form area. Disconnection is still the likely explanation of hemi-alexias, though, particularly when splenial lesions damage inter-hemispheric projections and cause left hemi-alexia. An intra-hemispheric disconnection causing right hemi-alexia is theoretically possible but seems very rare, with only a single report that has been challenged on the grounds of inadequate perimetry. We describe the case of PH, who had a severe reading deficit in her right hemifield. Detailed perimetry showed only a small relative hemi-scotoma along the horizontal meridian, while word reading was impaired over a much larger expanse of her right hemifield, in which object recognition was spared. Reading, lexical decisions, and perceptual discrimination of words were impaired in the right hemifield, and this extended to letters and numbers, with a trend to an effect on the perception of an unfamiliar script, namely Korean. On magnetic resonance imaging she had a large left lateral occipital meningioma with vasogenic edema of occipital white matter tracts. Functional magnetic resonance imaging showed that the visual word form area was located just anterior to the mass. Her perceptual abnormalities resolved after resection of the tumor. We conclude that right hemi-alexia exists and is most likely due to intra-hemispheric disconnection of occipital input to the visual word form area.(c) 2022 Elsevier Ltd. All rights reserved.
Keywords:
Reading
Pure alexia
Inferior longitudinal fasciculus
Words
Disconnection
Journal
IF:
3.3
Papers:
5.8K
Citations:
1.3W