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Rigidity Sensing Explained by Active Matter Theory
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DOI：10.1016/j.bpj.2011.08.023.png)
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Abstract
En 中文
The magnitude of traction forces exerted by living animal cells on their environment is a monotonically increasing and approximately sigmoidal function of the stiffness of the external medium. We rationalize this observation using active matter theory, and propose that adaptation to substrate rigidity results from an interplay between passive elasticity and active contractility.
Keywords:
SINGLE-CELL RESPONSE
TRACTION FORCES
STIFFNESS
STRESS
MUSCLE
ADHESIONS
BEHAVIOR
MODEL
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