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Risk of second primary cancer and death in patients with idiopathic inflammatory myopathies
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DOI：10.1016/j.semarthrit.2026.152997.png)
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Abstract
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• The risk of a second primary cancer within four years after a first post-idiopathic inflammatory myopathies (IIM) cancer diagnosis was low (<5%); being male and having a cancer history were strong risk factors. • A second post-IIM cancer modestly increased the baseline mortality risk, but mortality risk was markedly higher—approximately sixfold—in patients with dermatomyositis (DM) compared with non-DM IIM. • These findings enhance our understanding of the long-term cancer burden in IIM and may inform continued surveillance strategies among IIM cancer survivors.
Keywords:
Idiopathic inflammatory myopathies
dermatomyositis
polymyositis
subsequent malignancies
survival
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