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RNA localization: Different zip codes, same postman?

delete1998-10-01
delete120
PRE
AI
Y
Yuri Oleynikov *
R
Robert H. Singer
DOI：10.1016/S0962-8924(98)01348-8delete
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Abstract

Abstract

En 中文
RNA-localization mechanisms involve specific sequences in the localized RNA and proteins that bind to these sequences and mediate the interaction with cytoskeletal elements. Until recently, it seemed as though two separate types of mechanism were operating for mRNA localization - involving interaction with either microtubules or actin microfilaments. However, it is now clear that some of the protein components involved in mRNA localization can participate in both microtubule- and actin-dependent localization pathways. This, combined with new evidence for evolutionary conservation of some of these proteins, suggests a previously unanticipated uniformity in mRNA-localization mechanisms.
Keywords:
BICOID MESSENGER-RNA
ASYMMETRIC LOCALIZATION
BINDING PROTEIN
DROSOPHILA
PROSPERO
STAUFEN
YEAST
GENE
XENOPUS
SEGREGATION
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AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Trends in Cell Biology cover
Trends in Cell Biology
IF:
18.1
Papers:
3.1K
Citations:
2.0W

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No organization information available