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Ruptoblasts: Explosive cytotoxicity from an ancient lineage
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DOI：10.1016/j.tcb.2026.06.009.png)
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Abstract
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Cytotoxic immunity has long seemed the exclusive province of blood. Chai et al. challenge this view by describing ruptoblasts, glandular cells that explode on hormonal cues to kill neighbors across kingdoms. Ruptosis, their distinctive form of death, hints at an ancient immune logic that mainstream model organisms appear to have quietly lost.
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