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Safety and Immunogenicity of the Live-Attenuated Quadrivalent Dengue Vaccine V181 Compared With Butantan-DV Among Healthy Adults in Brazil: A Randomized, Double-Blind, Phase 2 Trial

delete2026-07-01
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OA
AI
D
David Alexanderian
F
Fabiano Ramos
S
Soumya Chatterjee
A
Alexandre Vargas Schwarzbold
A
Ana Paula Loch
A
Ariane Cristina Barboza Zanetti
Q
Qiuxu Chen
J
Jason Martin
M
Matthew T Onorato
G
Germán Áñez *
DOI:10.1093/cid/ciag349delete
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Abstract

Abstract

En 中文
Dengue is caused by infection with 1 of 4 dengue virus (DENV) serotypes (DENV-1 to DENV-4). V181 and Butantan-Dengue Vaccine (Butantan-DV) are independently developed, single-dose, quadrivalent dengue vaccines based on the same attenuated parental strains.

Journal

Clinical Infectious Diseases cover
Clinical Infectious Diseases
IF:
7.3
Papers:
2.6W
Citations:
7.8W

Organization

Instituto Butantan cover
Instituto Butantan
Scholars:
2.8K
Papers: 1.5K
Citations: 1.4K
M
Merck & Co., Inc.
Scholars:
871
Papers: 147
Citations: 0
Universidade Federal de Santa Maria cover
Universidade Federal de Santa Maria
Scholars:
361
Papers: 118
Citations: 5.4K
H
hospital são lucas da puc do rio grande do sul
Scholars:
2
Papers: 1
Citations: 0
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