Sage (Salvia spp.) as a multi-target resource for healthy aging: Current evidence and perspectives

Isabella Giacomini

doi:10.1016/j.mad.2026.112204

Sage (Salvia spp.) as a multi-target resource for healthy aging: Current evidence and perspectives

2026-05-28

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Isabella Giacomini

M

Miles Sarill

V

Veronica Cocetta

M

Monica Montopoli *

DOI：10.1016/j.mad.2026.112204

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• Eight representative Salvia species were reviewed for anti-aging potential. • Antioxidant and anti-inflammatory effects are the most consistent findings. • S. haenkei provides the strongest support for senescence-related activity. • Fibrosis and sarcopenia endpoints are emerging but remain underexplored. • Human evidence is limited and mainly derives from topical studies.

Keywords:

Salvia

Aging

Photoaging

Inflammaging

Senescence

Sage (Salvia spp.) as a multi-target resource for healthy aging: Current evidence and perspectives

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