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scafari: exploring scDNA-seq data
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DOI：10.1093/bioinformatics/btaf477.png)
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Abstract
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Recent advances in single-cell sequencing made it possible to not just analyze a cell's individual expression pattern, but to gain insights into a single cell's genome using the cutting-edge technology single-cell DNA sequencing. Mission Bio is, with the Tapestri platform, one of the few providers of this technology. So far, however, there is only little open-source software available for user-friendly processing and quality analysis of this data type. With scafari, we present a tool that offers easy-to-use data quality control as well as explorative variant analyses and visualization.Availability and implementation scafari is implemented as an R Bioconductor package featuring a shiny application and is available at https://bioconductor.org/packages/scafari.
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