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Screening MRI in Congenital EOS: Is It Safe to Delay Advanced Imaging to Decrease Early Anesthesia?
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DOI：10.1097/bpo.0000000000003177.png)
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Abstract
En 中文
Purpose:To quantify the prevalence of neural axial abnormalities in congenital early-onset scoliosis (C-EOS) patients stratified by age group, correlate prevalence of treatment, and determine if a delay in MRIs affects outcomes.Methods:A multicenter registry with data on 751 C-EOS patients was retrospectively reviewed, of which 659 patients were included. Data included demographics, pre-index major coronal curve, age at first MRI, intraspinal MRI findings, neurosurgical interventions and scoliosis fixation performed, intraoperative and postoperative complications, and unplanned return to the operating room (UPROR) for orthopaedic complications. Patients were divided into 2 cohorts utilizing age 3 as a cutoff. This age cutoff was selected based on an FDA warning of the potential neurocognitive effects of anesthesia used for MRIs in patients younger than 3 years. Spearman Rho correlations, independent t tests, and chi 2 tests were used for statistical analysis.Results:Patients were divided into 2 groups: first MRI younger than or equal to 3 years of age (n=277) and older than 3 years of age (n=382). One hundred thirty-three abnormal MRIs were identified (20%). There was no significant correlation between age at MRI and abnormal intraspinal findings (rs= -0.018, P=0.64). Among patients with abnormal MRIs, no correlation existed between age at MRI and UPROR. In this cohort, 23 neurosurgical procedures were performed and no significant difference was found in UPROR between groups (P=0.54). There were 3 neurologic complications in the younger than or equal to 3-year group and 0 in the older than 3-year group (P=0.07). No significant difference was found in mean pre-index major coronal curve (P=0.25).Conclusions:The prevalence of neural axis abnormalities in C-EOS was 20%. There was no significant correlation between age at first MRI and the chance of an abnormal MRI. There were no significant differences in neurological complications and UPROR between the younger than or equal to 3-year and older than 3-year groups. Thus, in C-EOS, MRI may be cautiously deferred until after the age of 3 in patients with normal neurological examinations and radiological findings.
Keywords:
congenital scoliosis
early-onset scoliosis (EOS)
spine deformity
anesthesia
magnetic resonance imaging (MRI)
neural axis abnormalities
Journal
J
IF:
1.5
Papers:
174
Citations:
9.1K
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