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Screening of botanical drugs against Metschnikowia bicuspidata and preliminary application in the “milky disease” of Eriocheir sinensis

delete2026-05-01
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PRE
AI
P
Peilin Zhou
J
Jieying Yu
周伟家 (Weijia Zhou)
王荣 cover
王荣 (Rong Wang)
Z
Zhouling Chen
K
Kexin Hao
L
Luxi Huang
S
Shigen Ye *
DOI:10.1016/j.jip.2026.108645delete
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Abstract

Abstract

En 中文
• Three botanical drugs—Mahonia bealei, Aucklandia lappa and Arisaema erubescens—were identified as potent inhibitors against Metschnikowia bicuspidata, a pathogen causing “milky disease” in Eriocheir sinensis. • The botanical drugs Mahonia bealei, Aucklandia lappa, and Arisaema erubescens disrupt the cellular integrity of Metschnikowia bicuspidata, inducing severe morphological deformation and cell damage, thereby exerting antifungal effects. • The three botanical drugs Mahonia bealei, Aucklandia lappa, and Arisaema erubescens significantly increased the survival rate of Metschnikowia bicuspidata-infected Eriocheir sinensis by 19.96%, 6.37%, and 15.48%, respectively, highlighting their potential as therapeutics for the control of “milky disease”
Keywords:
Mahonia bealei
Aucklandia lappa
Arisaema erubescens
Metschnikowia bicuspidata
Eriocheir sinensis

Journal

Journal of Invertebrate Pathology cover
Journal of Invertebrate Pathology
IF:
2.4
Papers:
3.7K
Citations:
7.3K

Organization

D
Dalian Ocean University
Scholars:
2.9K
Papers: 1.4K
Citations: 2.5K
I
institute for food and drug control
Scholars:
1
Papers: 1
Citations: 0
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