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Selective encapsulation by Janus particles
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DOI：10.1063/1.4922781.png)
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Abstract
En 中文
We employ Monte Carlo simulation to examine encapsulation in a system comprising Janus oblate spheroids and isotropic spheres. More specifically, the impact of variations in temperature, particle size, inter-particle interaction range, and strength is examined for a system in which the spheroids act as the encapsulating agents and the spheres as the encapsulated guests. In this picture, particle interactions are described by a quasi-square-well patch model. This study highlights the environmental adaptation and selectivity of the encapsulation system to changes in temperature and guest particle size, respectively. Moreover, we identify an important range in parameter space where encapsulation is favored, as summarized by an encapsulation map. Finally, we discuss the generalization of our results to systems having a wide range of particle geometries. (C) 2015 AIP Publishing LLC.
Keywords:
DRUG-DELIVERY SYSTEMS
MICROENCAPSULATION
NANOPARTICLES
ELLIPSOIDS
SPHEROIDS
KINETICS
BEHAVIOR
RELEASE
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