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Senescence-associated tertiary lymphoid structures in Sjögren's disease model nishiura mice
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DOI：10.1016/j.mad.2026.112213.png)
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Abstract
En 中文
• Autoantibody production and decreased saliva secretion in NI female mice. • Senescence-associated tertiary lymphoid structures in submandibular gland. • IgG production by B220 +/PD-1 + cells stimulated with SA-Tfh cells. • Expansion of tertiary lymphoid tissue through SA-Tfh cell transplantation. • Correlation between age of SjD patients and fibrogenic capacity per SA-Tfh cell.
Keywords:
B220⁺/PD-1⁺ cells Model Mice
Senescence
Sjögren's Disease
Tertiary Lymphoid Structures
Tfh cells
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