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Serum Mac-2 Binding Protein Glycan Isomer and Cerebral White Matter Injury in Older Adults: A Hepatic–Cerebral Link
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DOI：10.1111/hepr.70209.png)
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Abstract
En 中文
Metabolic dysfunction–associated steatotic liver disease (MASLD) is increasingly recognized as a systemic condition with extrahepatic complications; however, its impact on cerebral microvascular pathology remains poorly understood. This study aimed to examine the association between serum Mac-2 binding protein glycan isomer (M2BPGi), a validated biomarker of liver fibrosis, and cerebral small vessel disease (CSVD), as reflected by T1-weighted white matter hypointensity volume (WM hypointensity).
Keywords:
cerebral small vessel disease
hepatic–cerebral axis
liver fibrosis biomarker
M2BPGi
MASLD
white matter hypointensity
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